P. Iliev, I. Ilieva and C. StaciBitter gourd ranks first among cucurbits and has great demand in international market, but not to spread in the Republic of Moldova despite this a due attention has not been given towards a need-based crop improvement. There is a prime need for Bitter gourd to evaluate cultivars suited to specific agro-ecological conditions. Three different genotypes of bitter gourd (Momordica charantia L.) were evaluated concerning yield and yield contributing traits. All genotypes showed relevant results and can be cultivated in the Republic of Moldova climate conditions. The best results were obtained on Indian and local genotypes of bitter gourd.